Mukta gupta biography of christopher

  • The Honourable Ms. Justice Mukta Gupta, Delhi High Court, India; The Honourable Justice Derek Hartshorn, Supreme and National Courts, Papua New Guinea; Mr. Kent.
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    • The Honourable Mr. Justice Christopher Birch, High Court, Barbados
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    • mukta gupta biography of christopher

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      . Author manuscript; available in PMC: 2024 Mar 1.

      Published in sista edited struktur as: Cancer Epidemiol Biomarkers Prev. 2023 Sep 1;32(9):1146–1152. doi: 10.1158/1055-9965.EPI-22-1020

      Abstract

      Background:

      Individuals with adenomatous colorectal polyps undergo repeated colonoscopy övervakning to identify and remove metachronous adenomas. However, many patients with adenomas do not develop recurrent adenomas. Better methods to evaluate who benefits from increased surveillance are needed. We evaluated the use of altered EVL methylation as a potential biomarker for risk of recurrent adenomas.

      Methods:

      Patients with ≥1 colonoscopy had EVL methylation (mEVL) measured with an ultra-accurate methylation-specific droplet digital PCR assay on normal colon mucosa. The association between EVL methylation levels and adenoma or colorectal cancer (CRC) was evaluated using three case/control definitions in three models: unadjusted (model 1), adjusting for baseline characteristics (mod